I'm not sure quite what you're asking. Something like how you can create the equivalent of a data warehouse using QlikView? If so, I think the basic approach is to create a "warehouse" of QVDs that your applications load from instead of from your databases.
A good blog post on the basic idea is here, even if I'd disagree with some of the specifics:
http://www.quickqlearqool.nl/?p=1064
There's a discussion of the advantages of QVDs over reading directly from the databases here:
http://community.qlik.com/forums/t/16542.aspx
