we're facing an issue on Amazon Virtual Private Cloud. The installation in on a Windows 2012 Server with firewall turned off. In front of we've configured (traffic is open on port 443, 4244, 80 e 4248 ) the AWS load balancer to reach Sense machine from Internet. We've no problem to connect to the Qlik hub from the local network, but trying to connect to it via public network an issue is raised. After login form the hub report to have lost the connection.
There are actually quite a range of ports you may need to open up. We've found that we needed to have 443, 80, 4244 and 4248 that you have, but also 4241, 4242, 5050 and 5051 when deploying to AWS. One of my colleagues, Chris_Johnson has done a fair bit of work on this and may be able to advise further.