I guess so. Set the resolution of your monitor to 1280x800, hide the taskbar and maximise the QV Desktop to cover the entire screen area. Better not use the Windows maximise button, but you should drag the window borders (if there are any) to fit inside the screen area.
Note that this menu selection resizes the QV Desktop Window including all menus, toolbars, scrollbars, window borders and other chrome to cover an area of exactly that size. Pretty useless if you want to restrict the sheet area for display in for example the AJAX client.