I would like to ask why my Application/QVW when it open it always hang or Not Responding state I have Qlikview version 10 and Window Server 2008 R2 with 16GB RAM.
It depends on the way you have done the Data Modelling, calculations involved in charts etc. Try to Optimise the data model based upon the data you want.
Is the application not getting launched from starting itself or later on you are facing problems?
It's possible to compress a .qvw document (see the Compression setting on the General tab of the document properties window). But when loaded on QV Server it will be decompressed into RAM. That's necessary and unavoidable. You may have to add more RAM, but you also have to check if the server isn't CPU-bound. And that your document doesn't contain badly performing charts. See this blog post (and read the comments too) for example: Recipe for a Memory Statistics analysis
