Kevin, did you follow Sonja's guidance? There should likely be messages in the QMS logs regarding it not being able to contact the QDS service, and depending upon the version you are running, there may be a recommendation on what to do to address the issue. Let us know what you see.
To help users find verified answers, please do not forget to use the "Accept as Solution" button on any post(s) that helped you resolve your problem or question. I now work a compressed schedule, Tuesday, Wednesday and Thursday, so those will be the days I will reply to any follow-up posts.