From your model you have some isolated sets of data -
(Shipping Or.. & WMSOrganis...)
and (FlexSets & Flex Values)
Including values from either isolated datasets with fields from other data sets will create a cartesian join between the values which I guess is the cause of your slow response.
You either need to set the correct links between the tables in your model, or remove the fields that are causing the cartesian join from your charts.