When using a browser like Crome will automatically zoom in for you, based on your view port when you are on a high definition screen. In Qlik Sense Desktop 1.0 you see it in 100%, no zoom, which gives the behavior you are seeing.
We are looking at improvements around this.
Now Sense scales great in Sense desktop but you´ll get a "double" scale when using a browser like Chrome. This effect becoms quite annoying when using a high dpi tablet connected to Sense Server. On a traditional pc i can use Sense desktop but in the tablet I´m forced to use the browser.
We´re using a 10-inch tablet with the screen resolution 2560×1600