check my post, David
I did extensive testing and you situation might vary but I ended up with the following settings
hyperthreading is off, Enable HW prefetch, Enable NUMA, virtualization is off, Power set to High Performance, Turbo Boost is on
And I tested all combinations of these options above, was not fun!
Most of qlikview recommendation based on best practice indicates to turn Numa off & hyper-threading on for "E5" cpu's. I am surprised you have Numa on and hyper threading off.
Can you please provide details as to what you saw in each test with Numa On & OFF & similar with Hyper threading ON and OFF.
below is the article that talks about best practice.