Yes, of course. Every Microsoft Office installation comes with OLEDB(ODBC) drivers and a Jet engine to access various MS Office file formats with a query engine.
Fortunately, you don't have to install an MS Office license on your server to get your reload up and running. You can install the drivers as a separate package. See Re: Connect to Ms Access files? for a link to some older packages. Search the Microsoft Downloads site for newer drivers.
But of course, it could be something entirely different. What is the exact error message in the Document Log? If you can't find a Document Log, enable Settings->Document Properties->General->Generate Log File, save your QVW and rerun your server reload task.
Thanks for responding. I have installed the ODBC drivers for Office 2010 Suite from Microsoft but still get the following error at the end of my log:
0189 OLEDB CONNECT64*Provider*Password*Password*
Error: ErrorSource: Microsoft Access Database Engine, ErrorMsg: Could not find installable ISAM.
General Script Error