fortunately, Sense is adaptable to screen sizes. You can define in many ways what elements should work as "responsive" and what elements should not - when you leave the "auto" setting, it will be managed in a flexible way, depending on the screen size. If you specify custom settings, for example the exact placement of a Legend, then it is likely to remain there, even if the screen size should be smaller.
Beyond that, the responsive behavior is not very much customizeable. You can't apply scroll bars. Try to keep your screens relatively "un-busy" if you expect to have some screen with low resolution. If the screen is packed with controls, it's going to be very difficult to present nicely on a small screen.
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