I you application or server had a problem, we could check the log.
I don't think a new version of Office could generate a problem, unless you save the file in a different format ( .xlsx instead of a .xls). In this case, you need to rewrite part of your script.
QlikView can read Excel files even if Office is not installed on the machines.
For the document log, on QV Desktop go to Settings -> Document Properties -> General Tab - > check the 'generate log file' box
After reload, a file with the same name of the qvw will be generate in the same folder as the qvw with the extension QVW
so if you have the qvw:
the log file will be:
Sometimes windows will just hide the extension and change the icon to a text file icon, just look for something like this.
Hope it helps,