As far as i know every instance is unique per the user in qlikview. This is more of like you are trying to publish your changes to the app (Write-Back).
Variables will hold the information for that session per user basis. So there is no straight forward way of saving your changes to the app.
One way of doing it by Capturing the changes and writing back to a database/text/excel file and re-pulling the data into qlikview.
You can use Macro's or extension using webservice to do this job.