I am getting attached error while accessing QMC from local system(through http://xyz.abcd.net:4780/QMC/Default.htm). However, with local host that is in Microsoft server 2012, its working fine. Please let me know what could be the issue
use/configure localhost as the QMC host when working on the QlikView server machine itself, and use the domainname as host when working from a different machine, or
add http://xyz.abcd.net to the Trusted sites list in your browser configuration.
The cause of your problems accessing QMC using that URL is probably that your browser doesn't trust that URL and disables JavaScript for untrusted sites. Localhost is always free of suspicion...