Yes you can. Qlik Sense actually delivers two waterfall objects. The first one that you already mentioned works with measures you add to reach a final amount. There is a second object in the custom objects called variance waterfall (you must have installed the visualization bundle beforehand). This object allows you to display the variance between two kpis according to each element of a given dimension. There you go.
I am not sure about you're trying to acheive here but maybe you can provide more detail about your context. What is it exactly you want to do? It seems to me you might need to use set statements in each KPI to address the dimension requirement but again more context would be helpful.
