In Talend version 6.4.1, if you have a Route using the cRest component, and the endpoint is dynamically selected using the Apache Camel parameter DESTINATION_OVERRIDE_URL, the endpoint does not dynamically change unless maxClientCacheSize is explicitly set at 0 for the cRest component.
Root Cause
This is a Camel regression from version 2.17.0. Bug report CAMEL-12252 was opened with Apache.