You would need to create a UDC (user directory connector) to the local machine's repository. Then you can run a sync to sync the users and groups into Qlik Sense , and then they will show in the 'Users' section of the QMC and can referenced for token allocation
But when the user's login, they may get auto-authenticated to your domain credentials. To break that , you may need to login to the machine's IP address; https://<IPaddress>/hub and then it will prompt for credentials. Enter MachineName\UserName to ensure windows authenticates against the local directory, then you should get in as a local user. One issue though, Qlik sense will prevent access via IP until you add the IPaddress to the 'websocket origin white list' in the advanced properties of the Qlik Sense virtual proxy in the QMC. Post back if you run into any problems.