As a work around, you could use REPLACE() functions for your multiple symbols to replace all of them with a consistent character, like '-', and then use that single character in the NullInterpret variable.
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Data: LOAD * , If(IsNum(Value),Value,Null()) as Value1, If(IsNum(Value),Value,Null()=0) as Value2, If(Value='.' or Value='-' or Value='+',Null(),Value) as Value3, If(Value='.' or Value='-' or Value='+',Null()=0,Value) as Value4 INLINE [ Value, Sno 66, 1 55, 2 44, 3 44, 4 ., 5 -, 6 +, 7 33, 8 2, 9 ];
Null()-203408.qvw 149.5 K