Adding 22 dimensions to a straight table sounds like a very bad idea. QlikView must then evaluate all combinations of all distinct values, which will be a huge number and of course will take time. As a rule of thumb, you should avoid charts with more than 4 dimensions - and even that may sometimes be too many.
What you could do, is to use a field with a very fine grain as dimension, i.e. a field that has many distinct values and that "determines" the value of other fields. One example could be OrderLineID. Then you add the other fields as expressions: Only(Product), Only(Customer), etc. This way you could have many columns in a straight table, and still have it fast.
But 22 columns is still not meaningful - The user will not have any overview and will not learn anything from data. So, I think you should reconsider and put the 22 fields in different objects, probably even on different sheets.
HIC
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